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About Heart Failure

Heart failure is a serious condition in which the heart fails to pump blood effectively. This causes the blood flow to decrease to muscles, tissues, and organs throughout the body. It also causes blood to back up into the veins that return blood to the heart. The pumping efficiency of the heart may be weakened by a heart attack, by diseases affecting the heart muscle, by mechanical problems with the heart valves, by prolonged high blood pressure, or by abuse of drugs or alcohol.

Heart failure is the leading diagnosis and cause of death due to heart disease in recent years, with about 3 million Americans (1% of the U.S. population) affected. It is the number one reason for hospitalization admissions in people over age 65.

However, the good news is that more people are learning how to reverse heart failure with an aggressive cardiorespiratory rehabilitation program including exercise, dietary changes, medications, and other lifestyle changes. In this section, you'll learn about the latest medical findings and where to get more information about heart failure.

Information for this section taken from: Mayo Clinic Family Health Book, William Morrow and Company, Inc., 1990; K. Weber et al., "Exercise Testing in the Evaluation of Cardiopulmonary Disease," Clinics in Chest Medicine 5 (March 1984); Journal of the American College of Cardiology 1996;27:345-52; Success with Heart Failure: Help and Hope for Those with Congestive Heart Failure, Marc A. Silver, M.D., Insight Books (a division of Plenum Publishing Corporation), 233 Spring Street, New York, NY 10013-1578, 1994.


Signs and symptoms of heart failure

  • Swollen ankles; if bedridden, swelling in lower portions of the back
  • Shortness of breath (during activities and/or shortly after lying down in bed at night)
  • Weakness and fatigue
  • Chest pains
  • Weight gain or loss
  • Changes in appetite
  • Inability to shake a cold or other minor illness

Diagnosing heart failure

Heart failure causes a feeling of weakness and fatigue. Routine physical activities such as climbing stairs become difficult to perform. A person with heart failure will also have trouble breathing after exerting themselves such as when exercising. In advanced stages, a person will feel short of breath when lying down in bed. You will need to elevate your head on several pillows to sleep comfortably.

If you have early warning signs of heart failure such as shortness of breath and fatigue, talk to your doctor. He or she may give you a number of diagnostic tests including a test for ejection fraction (the amount of blood the heart ejects or pumps with each contraction) and a test for oxygen consumption (how the heart and lungs work together to provide blood and oxygen to your body).

Because one of the key symptoms of heart failure is exercise intolerance, a cardiopulmonary exercise test gives the most useful information about how the heart, lungs, blood vessels and muscles work are working together. In this test, you will take a standard exercise test while breathing through a mouthpiece that measures your breath during exercise. The system's computer will simplify this information into a value called VO2max representing your body's oxygen consumption at maximal exercise. You can compare your value to the following chart:

 VO2max (ml/min/kg)
Functional Class 
 Performance Comparison

 Normal range(1)
60-80
40-59
30-39
21-29

 A


Elite
Well-Trained
Conditioned
De-Conditioned
Training Program Recommended

 16-20

 B  Mild to Moderate
Cardiopulmonary Disease
May need rehabilitation and medical therapy; may be early for surgery

 10-15

 C  Moderate to Severe
Cardiopulmonary Disease
Potential surgery candidate (2)

 6-9

 D Severe Cardiopulmonary Disease
Surgery candidate (2)

 <6

 E Critical Cardiopulmonary Disease
Significant risk for surgery (2)

(1) - Normal range values decline with age, are lower for women than men, and are lower when testing is performed on a cycle instead of a treadmill
(2) - Assuming that underlying disease has surgical implications


Therapy

Exercise

Although people with heart failure need lots of rest, this does not mean you should spend all day in bed. While restricting activity may reduce burden on the heart, it also produces a severe deconditioning of the heart and other muscles. Many heart failure experts are now commonly encouraging their patients to embark on an aggressive cardiac rehabilitation training program.

Your doctor may give you an individualized exercise program which, when combined with medication, has helped many patients get better without surgery. Do not begin an exercise program without first talking to your doctor.

For more information about exercise and the American College of Sports Medicine's guidelines for exercise, click here to reach "All About Exercise".

Diet

  • Restrict salt intake
  • Avoid alcoholic beverages
  • Reach and maintain a weight appropriate for your height and build

Medication

Heart failure is often treated with drugs in combination with exercise and other lifestyle changes. Common medications are diuretics; digoxin; and angiotension-converting enzyme inhibitors, or ACE inhibitors.

Diuretics, sometimes called water pills, are also used to treat mild cases of high blood pressure. They increase the rate your body eliminates urine and salt, thereby decreasing the load on your lungs and the swelling in your legs. In addition to salt loss, potassium is also eliminated, so your doctor will monitor your blood potassium level and prescribe a supplement if necessary.

Digoxin increases the strength of the heart's pumping, and is especially useful if your heart failure is caused by a systolic heart rhythm problem.

The newest form of drug therapy for heart failure, ACE inhibitors, also called vasodilators, dilate arteries to reduce the work the heart has to do and thereby allowing it to pump blood more effectively.

Surgery

Surgical treatment for heart failure is the exception rather than the rule. However, some cases of heart failure require surgery. For example, you may require surgical repair of damaged heart tissue or a heart valve replacement. For people with myocarditis or cardiomyopathy, heart transplantation may be an option.

The American College of Cardiology (ACC) recommends that all patients being considered for heart transplantation go through their recommended evaluation, which includes an exercise stress test with oxygen consumption (VO2max). The ACC's guidelines are as follows*:

I. Accepted Indications for Transplantation

1. Maximal VO2 < 10 ml/kg per min with achievement of anaerobic metabolism (the point at which the body has reached maximal aerobic capacity and can no longer perform work aerobically)

2. Severe ischemia (chest pain) consistently limiting routine activity not amenable to bypass surgery or angioplasty

3. Recurrent symptomatic ventricular arrhythmias refractory to all accepted therapeutic modalities

II. Probable Indications for Cardiac Transplantation

1. Maximal VO2 <14 ml/kg per min and major limitation of the patient's daily activities

2. Recurrent unstable ischemia not amenable to bypass surgery or angioplasty

3. Instability of fluid balance/renal function not due to patient noncompliance with regimen of weight monitoring, flexible use of diuretic drugs and salt restriction

III. Inadequate Indications for Transplantation

1. Ejection fraction <20%

2. History of functional class III or IV symptoms of heart failure

3. Previous ventricular arrhythmias

4. Maximal VO2 >15 m/kg per min without other indications

* JACC Vol. 22, No. 1, July 1993: 27.

As you can see, peak oxygen uptake (VO2max) <14 ml/kg per min is used as the primary indicator of whether a person needs a heart transplant. However, peak oxygen uptake is affected by a person's age, gender, and weight. More recently, doctors at the Saint Louis University School of Medicine published findings that if heart failure patients achieve greater than 50% of their predicted VO2max they can safely defer transplantation (JACC, 1996; 27:345-52). Your doctor will rely on a number of published charts showing predicted values based on a person's age, weight, and gender.



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