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Case Study:

CPX Testing for Exercise Prescription in Cardiac Rehabilitation

The patient, a 61-year-old, 78 kg. male, was referred for cardiac rehabilitation exercise training. The patient's risk factors for coronary artery disease included an elevated triglyceride value and low HDL cholesterol. He had a prior history of anterior myocardial infarction followed by 3-vessel coronary artery bypass surgery. His immediate post-operative course was complicated by congestive heart failure. Upon resolution of the acute CHF, his physician felt he could benefit from an organized cardiac rehabilitation program.

A cardiopulmonary exercise (CPX) test with respiratory gas exchange measurements was performed on this patient to prescribe a level of exercise that would be both safe and provide cardiovascular training benefit. The patient's medications at the time of the CPX test included Aspirin, Lanoxin, and Lopid.

The patient performed a maximal treadmill CPX test using the Bruce protocol, with the results below:

Parameter Actual Patient Value Normal Value
Max Heart Rate 160 (101% of age-predicted max) 159
VO2max 28.1 ml/kg/min (=8.0 METS)
VO2 max/Pred. VO2 max 90% >85%
Max 02 Pulse 13.7 ml/beat 15.3 ml/beat
VO2 at AT 21.3 ml/kg/min (=6.0 METS)
HR at AT 122
Work Rate at AT 2.5 mph, 12% grade
VO2 AT/Pred. VO2 max 69% >40%
Breathing Reserve 53% >30%

The patient demonstrated normal maximal aerobic capacity with no evidence of clinically relevant cardiac or pulmonary limitations to exercise tolerance. He demonstrated normal BP response to exercise with a resting BP of 136/90 to a max exercise BP of 152/86. ST-segment changes during his test could not be interpreted due to Digoxin (Lanoxin) therapy and a partial left bundle branch block. Target exercise heart rates were therefore prescribed using respiratory gas exchange measurements as described below:

  • Exercise heart rate: 122 b/min (HR at AT=122)
  • Heart rate not to exceed: 144 b/min (HR at onset of terminal hyperventilation)
  • MET level for exercise: 6.0 METS

He commenced exercise training with positive benefits and no cardiopulmonary complications.

Acknowledgement

Neil F. Gordon, MD, PhD; Christopher Scott, MSS, MS, The Heart and Lung Group of Savannah and The Center for Heart Disease Prevention, Candler Hospital, Savannah, Georgia.


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